Discovery of LC-SF-14, a selective dual inhibitor of SHP2 and FGFR for the treatment of FGFR2-driven gastric cancer

作者：Lei Zheng, Yuhan Wang, Zheng Jiang, Shiyan Chen, Shiyan Chen, Xiansheng Cao, Xiaohao Huang, Ruixiang Luo, Lulu Zheng, Qin Li, Linglan Tu, Guang Liang, Guang Liang, Lingfeng Chen · 发表于：European Journal of Medicinal Chemistry · 年份：2025 · DOI：10.1016/j.ejmech.2025.117745 · 被引用次数：8 · 研究领域：Fibroblast Growth Factor Research、Protein Tyrosine Phosphatases、Proteoglycans and glycosaminoglycans research