Effectiveness of CONUT and NRI as nutritional risk screening tools in peritoneal dialysis: a multicenter study

作者：Wenlong Qiu, Rui Chu, Yaqi Ma, Jiaxuan Xue, Qingdong Xu, Yueqiang Wen, Xiaojiang Zhan, Fenfen Peng, Xiaoyang Wang, Juan Wu, Ning Su, Xiaoran Feng, Xingming Tang, Xianfeng Wu, Qian Zhou, Na Tian · 发表于：Frontiers in Nutrition · 年份：2025 · DOI：10.3389/fnut.2025.1544338 · 被引用次数：4 · 研究领域：Dialysis and Renal Disease Management、Nutrition and Health in Aging、Parathyroid Disorders and Treatments

Background Nutritional risk is a significant concern for patients undergoing peritoneal dialysis (PD), adversely affecting their quality of life and increasing the risk of infections and complications. Effective screening tools are needed to identify high-risk patients for targeted interventions. This study investigates whether different nutritional assessment methods, like the Controlling Nutritional Status (CONUT) score and Nutritional Risk Index (NRI), correlate with patient prognosis, highlighting the importance of selecting appropriate screening tools to improve clinical outcomes in PD patients. Methods This multicenter retrospective cohort study initially collected data from 2,427 patients across 10 centers, but ultimately included a cohort of 2,105 PD patients to evaluate the prevalence of malnutrition assessed using both the CONUT and NRI and its independent effects on all-cause mortality. Statistical analyses included log-rank tests, Cox regression models and the receiver operating characteristic curves to evaluate the association between nutritional risk and mortality. Results Our findings revealed that 76.58% of patients were classified as having nutritional risk according to the CONUT score, while 79.10% by the NRI. Patients with nutritional risk exhibited a significantly higher all-cause mortality rate (log-rank test, p < 0.001). Cox regression analysis demonstrated that severe nutritional risk was an independent predictor of all-cause mortality, with adju...