Factors influencing medication adherence for deep vein thrombosis prevention in post-discharge patients after joint replacement surgery: a qualitative study based on Protection Motivation Theory

作者：Feng Fu, Jing Jiang, Wenchao Gu, Leijiang Li, Jing Zhang, Xiurui Deng, Chao Liu, Lingyun Tian, Yinglan Li · 发表于：BMJ Open · 年份：2025 · DOI：10.1136/bmjopen-2024-090983 · 被引用次数：9 · 研究领域：Total Knee Arthroplasty Outcomes、Venous Thromboembolism Diagnosis and Management、Atrial Fibrillation Management and Outcomes

OBJECTIVES: This study aims to identify factors influencing medication adherence for deep vein thrombosis (DVT) prophylaxis in post-discharge patients after joint replacement surgery using Protection Motivation Theory (PMT). DESIGN: This study employed qualitative semi-structured interviews with patients discharged after hip or knee replacement surgery. SETTING: Using purposive sampling to ensure a diverse representation of patient profiles, participants were recruited from patients who underwent total knee replacement surgery from April 2024 to May 2024 and were discharged 1-month prior. PARTICIPANTS: 12 patients who had undergone total knee replacement surgery participated in the study. The median (IQR) age of participants was 57.5 (55-67.25) years. ANALYSIS: Semi-structured interviews were conducted via online video calls. These interviews were audio recorded and transcribed verbatim. Data were analysed using Colaizzi's seven-step method. Themes were identified based on the dimensions of the PMT: susceptibility, severity, internal rewards, external rewards, response efficacy, self-efficacy and response costs. Two researchers independently coded and extracted themes, with discrepancies resolved through team discussions and verification with respondents. RESULTS: Participants acknowledged the importance of adhering to anticoagulant medication to prevent DVT and its complications, understanding the severe consequences, such as the life-threatening nature of pulmonary embolism...