Long-Term Antibacterial and Antimildew Polyacrylate-Based TCS@ZIF-8 Leather Coatings Based on Encapsulation and Slow-Release Effects

作者：Jianzhong Ma, Chunyan An, Lei Zhang · 发表于：ACS Applied Materials & Interfaces · 年份：2025 · DOI：10.1021/acsami.5c02719 · 被引用次数：8 · 研究领域：Antimicrobial agents and applications、Luminescence and Fluorescent Materials、Covalent Organic Framework Applications

In this work, we synthesized an acid-responsive zinc metal–organic framework (ZIF-8) at room temperature by a solvent method, which can not only be used as an antibacterial by releasing zinc ions but also as a carrier for antibacterial material encapsulation. Subsequently, the broad-spectrum antibacterial triclosan (TCS) was encapsulated in ZIF-8 by the impregnation method, and a long-term antibacterial and antimildew material with slow-release effect TCS@ZIF-8 was synthesized successfully. The encapsulation rate and drug loading rate of TCS@ZIF-8 prepared by adjusting the mass ratio of ZIF-8 and TCS were 71.9 and 25.1%, respectively. Further, TCS@ZIF-8 was introduced into polyacrylate (PA) emulsion, and PA/TCS@ZIF-8 nanocomposite emulsion was prepared successfully by the physical blending method. When the pH of the coating surface became slightly acidic due to the metabolic byproducts of microbial growth, ZIF-8 in PA/TCS@ZIF-8 disintegrated to release Zn 2+ and TCS, which can effectively kill bacteria and mold. When the dosage of TCS was 4.0 wt %, the antibacterial rate of the PA/TCS@ZIF-8 nanocomposite film against Escherichia coli and S. aureus was 100 and 97.3%, respectively. Finally, PA/TCS@ZIF-8 nanocomposite emulsion-coated leather was prepared by the spraying method. Compared with the control group that did not use ZIF-8-encapsulated TCS, PA/TCS@ZIF-8 nanocomposite emulsion-coated leather not only showed better antibacterial and antimildew effects but also showed long...