Study of conductive nerve conduits for anti-inflammatory and antioxidant effects

作者：Runtian Xu, Hanping He, Huan Deng, Yuehan Dong, Xiangjie Wu, ZY Xia, Yang Zhou, Lin Yang, Zhijun Huang, Wenjin Xu, Peihu Xu, Haixing Xu · 发表于：RSC Advances · 年份：2025 · DOI：10.1039/d5ra00997a · 被引用次数：4 · 研究领域：Neuroscience and Neural Engineering、Nerve injury and regeneration、Lipid Membrane Structure and Behavior

, meeting the requirements for nerve repair. The lack of cytotoxicity and the anti-inflammatory and antioxidant properties of l-ZBZPGM were demonstrated using RSC96 cells and Raw264.7 cells. Additionally, through electrical stimulation experiments, it was proven that the addition of GO can promote the proliferation of nerve cells. The biological materials used in this study are of simple composition, and their degradation products may have a minimal impact on the microenvironment. The findings suggested that l-ZBZPGM was more conductive to peripheral nerve regeneration.