Mechanisms of pulmonary fibrosis and lung cancer induced by chronic PM2.5 exposure: Focus on the airway epithelial barrier and epithelial-mesenchymal transition

作者：Yuyu Shi, Qi Shao, Zilin Ren, Guojiao Shang, Jinhua Han, Jialin Cheng, Yuxiao Zheng, Fafeng Cheng, Changxiang Li, Qingguo Wang, Xueqian Wang · 发表于：Ecotoxicology and Environmental Safety · 年份：2025 · DOI：10.1016/j.ecoenv.2025.118253 · 被引用次数：6 · 研究领域：Air Quality and Health Impacts、Chronic Obstructive Pulmonary Disease (COPD) Research、Biomarkers in Disease Mechanisms

-related lung diseases from four aspects-anti-inflammatory and antioxidant drugs, signaling pathway inhibitors, non-coding RNA-targeted therapies, and gene editing and cell therapies-by focusing on the two key links of the airway epithelial barrier and EMT.