Long-term effects and effect heterogeneity of lifestyle and metformin interventions on type 2 diabetes incidence over 21 years in the US Diabetes Prevention Program randomised clinical trial

作者：William C. Knowler, William C Knowler, Lindsay Doherty, Sharon L. Edelstein, Peter H. Bennett, Dana Dabelea, Mary A. Hoskin, Steven E. Kahn, Rita R. Kalyani, Catherine Kim, F. Xavier Pi‐Sunyer, Sridharan Raghavan, Vallabh O. Shah, Marinella Temprosa, Elizabeth M. Venditti, David M Nathan, Caroline Abbas, Kathy Abbott, Solome Abebe, Ronald T. Ackermann, Kelly J. Acton, Karwyn S. Adams, Daphne T. Adelman, Elsie Adorno, Nnenna Agharanya, Khan Akbar, John Albers, F.Alan Aldrich, Teresa Alexander, Adrienne Allen, David B. Allison, David Altshuler, Denise R. Anderson, Ellen Anderson, Harelda Anderson, Natalie Andon, Vickie L. Andre, William B. Applegate, Richard F. Arakaki, Jennifer Arceneaux, Ronald A. Arky, Vanita Aroda, Nancy J. Aronoff, Leslie F. Atler, Raymond Bain, Narleen K. Baker-Ladao, Maria Baldo, Larry B. Ballonoff, Julie Bamdad, Rosalyn Barber, Melanie Barkalow, Susan Barr, Nancy Barrett, Elizabeth Barrett-Connor, Sarah Bassiouni, Heather Baumhauer, Catherine Bavido-Arrage, Ralph Beddow, Shandiin Begay, Catherine Behrends, Madeline Beltran, Catherine Benchoff, Peter H. Bennett, MaryBeth Benson, Wendy Benz, Nina E. Bermudez, Joel Bethepu, Tsedenia Bezabeh, Liana K. Billings, Evelyn C. Bird, Laurie Bissett, Barbara Blodi, Geraldine Boggs, Kristy Bondi, Miriam Boraz, Medhat Botrous, Alexis Bouffard, Anna Bowers, Patrick J. Boyle, Vanessa Bradley, Frederick L. Brancati, Michael Brändle, George A. Bray, Tina Brenneman, Marjorie Bronsord, Brenda A. Broussard, Ernestine Brown, Arleen Brown, Angela L. Brown, Janet O. Brown, Morton B. Brown, Marybeth Bryant, Michael Bryer-Ash, Brian C. Bucca, Maria Budget, Matthew Budoff, Mark R. Burge, Jacqueline P. Burke, Nicole Butler, Enrique Caballero, Enrico Cagliero, Jackie Callaghan, Karen M. Callaphan, Jeanette Calles, B.Ned Calonge, Charles Campbell, Janene L. Canady, Carolyn M. Cantrell, Sharon Cappelli, Jose F. Caro, MaryLou Carrion-Petersen, Caitlin E. Carter, Adrian Casillas, Paul Cassanova-Romero, Sumaya Castillo-Florez, Lisa Chai, Catherine M. Champagne, Michelle Chan, Jeanne B. Charleston, Annie Chatellier, Marcella Chavez, Wayman W. Cheatham, Ling Chen, Helen Chong, Costas Christophi, Kathy Chu, Lauren N. Claravall, Bart Clark, Debra Clark, Jeanne M. Clark, Lisa Clifford, Holly Cohn, Susan Cola, Celeste Colegrove, Kathleen Colleran, Claudia Conzues, Norman Cooeyate, Sherron Cook, Michelle Cook, Ellie Corkery, Liane Cox, Jill P. Crandall, Iris W. Culbert, Rebecca Culyba, Jeff Curtis, Kirsten Czech, Kali D'Anna, Dana Dabelea, Tara Dacawyma, Samuel Dagogo-Jack, Chris Dailing, Ronald Danis, Christine Darwin, Samia Das, Kristin David, Matthew Davis, Mary deGroot, Linda Delahanty, Lynne Delve, Catherine DeSandre, Lorna Dias, Charlotte Dodge, Lindsay Doherty, Kristi Dohm, Jennifer Dolgoff, Amitha Domalpally, Richard P. Donahue, Brittnie Dotson, Yolanda F. Dotson, Matthew S. Doughty, Jonalle M. Dowden, Amber Dragg, Helena Duffy, Crystal Duncan, Roberta Duncan, Gregory M. Dwyer, R. Eastman, Barbara Eberhardt, Steven V. Edelman, Sharon L. Edelstein, Cyndy Edgerton, David A. Ehrmann, Deborah Elsas, Ryan Endres, Samuel Engel, Alvera Enote, Cindy Evans, Gregory Evans, Andy Ewen, Martha Farago, Barbara Fargnoli, Basma Fattaleh, Edwin S. Fineberg, Edwin Fisher, Marian Fitzgibbon, Hermes J. Florez, Jose C. Florez, Ateka Fondino, Sandra T. Foo, Mary Foulkes, Sarah Fowler, Judith Fradkin, Therese Franklin, Paul W. Franks, Marlene Frazier, Janice Freel, Allison Friedler, Sandra L. Frieson, Wilfred Fujimoto, Megan Fultz, Kevin Furlong, Deanna Gabrielson, Kishore M. Gadde, Vonnie Gama, Om P. Ganda, Ted Ganiats, Yuping Gao, Sanford Garfield, Rajesh Garg, Pranav Garimella, Jacqueline M. Ghahate, Anna Giannella, Peggy Gibbs, Mimi M. Giles, Ryan Gilligan, Bonnie Gillis, Justin Glass, Martia Glass, Dorothy Gohdes, Ronald B. Goldberg, Valerie Goldman, Barry J. Goldstein, Angela Goldstein, Ysela Gonzales, Robert Gooding, Adrienne Gottlieb, Anne Goulding, Wendy Grant, Elaine Grassa, Alicia Greene, Frank Greenway, Edward Gregg, Kristina L. Grimes, Erik Groessl, Nisha Grover-Fairchild, John C. Guare, Ashley Guidi, Mathew Guido, Fonda G. Guillory, Stephanie Guimond, Lindsery Gurry, Angela Hadden, Steven M. Haffner, Lori Haffner, Susan Hagamen, Sharon Hall, Richard F. Hamman, Ethel Faye Hampton, Robert L. Hanson, Maegan Harden, Susan Harrier, Louann Harris, Jessica Harting, Monica Hartmuller, Kathy Hattaway, Helen P. Hazuda, Deloris Heard, Claire Hemphill, Robert R. Henry, Susan Hensley, April A. Herbert, William H. Herman, Doris A. Hernandez-McGinnis, Ruthanne Hilbrich, James O. Hill, Sherita Hill Golden, Marie-France Hivert, Heather Hoffman, Ashley Hogan Tjaden, Katherine Horak, Javiva Horne, Ellie Horse, Edward S. Horton, Tamara Horwich, Mary A. Hoskin, Crystal J. Howard-Century, Shelley R. Hoyer, Julie Hu, Larry Hubbard, Emma Hurt, Cynthia Hurtenbach, Penny Hyde, Uzoma Ibebuogu, James M. Ignaut, Raed Imseis, Louise E. Ingraham, Jillian Inouye, Juan Isaac, Mae K. Isonaga, Kathleen Jablonski, Merry Jackson, Marcia A. Jackson, Sharon D. Jackson, Alan M. Jacobsen, Robert Janicek, Priscilla Jay, Michael L. Jeffirs, Susan Jeffries, Tonya Jenkins, Dawn Jiggetts, Sujata Jinagouda, Carolyn Johannes, Deloris Johnson, Mariana K. Johnson, Cheryl K.H. Johnson, Samantha Johnson, Steve Jones, Tara L. Jones, Tracy Jones, Bonnie T. Jortberg, Hope Joseph, Steven E. Kahn, Roylen S. Kaskalla, Patricia Katz, Richard Katz, Naomi Katzir, Karen Kavena, Lisa Keasler, Tracy Kellum, Susie M. Kelly, Kim Kelly-Dinham, Betty M. Kennedy, Michelle Kerr, David Kessler, Prajakta Khare-Ranade, Anthony Killeen, Carolyn King, Lascelles Kirby, Marion S. Kirkman, Abbas E. Kitabchi, Stacey Kloiber, Robert H. Knopp, William C. Knowler, William C. Knowler, Kathleen M. Kobus, Margaret Kocal, Gaye Koenning, Preethy Kolinjivadi, Jonathan Krakoff, M.Kaye Kramer, Andrea M. Kriska, Nolan D. Kuenster, Lyn M. Kula, Jason Kurland, John M. Lachin, Blandine Laferrere, Milvia Lagarda, Lori Lambert, Helen Lambeth, Marycie Lamkin, Olga Lara, Mary Larkin, Carmen Larreal, Diane Larsen, Michael D. Larsen, Renee W. Latimer, Daniel Lawrence, Kathleen E. Lawton, Fernelle Leandre, Sarah Ledbury, Jane E. Lee, Christine Lee, Dione Lenz, Lilia Leon, Diana Leos, Claresa Levatan, Erma Levy, Yabing Li, Renee Liberoni, Lynne C. Lichtermann, Milajurine Lindsay, Edward W. Lipkin, Monica Lockett, Kimberly Loman, Nadege Longchamp, Carlos Lorenzo, Peter Lou, Holly Love Burkott, Jennifer C. Lovejoy, Anne Lowe, Jose A. Luchsinger, Jennifer Lukin, Megan Lyman, Yong Ma, Michelle Magee, Perpetua Magpuri, Maureen A. Malloy, Qurashia Manjoo, Jennifer Manly, Catherine Manus, Santica Marcovina, Michelle Marr, David G. Marrero, Arlene Martinez, Helen Martinez, Kieren J. Mather, Nestoras Mathioudakis, Margaret J. Matulik, Marjorie K. Mau, Elizabeth Mayer-Davis, Gina McAtee, Cherie McCabe, Kyle McDaniel, Charles McKitrick, Valerie McLymont, Audrey McMaster, Wylie McNabb, David McPherson, Lee E. Melancon, John S. Melish, Jadell Mendez, Jewel Mendoza, Boyd E. Metzger, Sara Michaels, Roeland J.W. Middelbeek, Julia Middendorf, Kathy Mikami, Marsha Miller, Margaret Mills, Pharis Mohideen, Mark E. Molitch, Maria G. Montez, Brenda K. Montgomery, Robert R. Moran, Tina Morgan, Ivy Morgan-Taggart, Laura H. Morris, Henry Mosley, Pamela Mucik, Sunder Mudaliar, Marielle Mugford, Monica Mullen, Rhea Mundra, Medha Munshi, Anne Murillo, Carmen Muro, Mary E. Murphy, Dawn Myers, Asha K. Nair, Patricia V. Nash, Yolanda Nashboo, Camille Natewa, David M. Nathan, Caroline Navy, Noemi Neira, Julie A. Nelson, Kathy Ngo, Maryanne Nicosia, Thomas Nilan, Alicia Noel, Ebenezer A. Nyenwe, Matthew O'Brien, Erin O'Kelly Phillips, Dan O'Leary, Kayla O'Neal, Sharon K. Odom, Hooman Oktaei, Cathryn F. Oldmixon, Jerrold M. Olefsky, Trevor Orchard, Robert Orlosky, Amy Otto, Jeong Pak, Carmen Pal, Lisa Palermo, Jocelyn Pan, Qing Pan, Jean Park, Kathy Parkes, Maureen Passaro, Avnisha Patel, Nancy Pemberton, MaryBeth Pena, Samsam C. Penn, Constance Pepe, Carol A. Percy, Leigh Perreault, Arlette Perry, Raynette U. Perry, Jessica Pettigrew, Kisha L Pinner, Christopher Piromalli, F. Xavier Pi-Sunyer, Thomas Pitts, Catherine S. Poirier, Steven Poirier, Evette Polczynski, Toni I. Pollin, Kenneth S. Polonsky, William Polonsky, Dorothy Pompi, Beverly D. Porter, Alexandra Poulos, Danielle Powell, David W. Price, Melvin J. Prince, Ronald J. Prineas, Paula Putenney, Marizel Quitingon, Riley Rainville, Hannah Rapoport, Amer Rassam, Robert E. Ratner, Pentti Rautaharju, Farida Rautaharju, Elyse Raymond, Susan Reamer, Judith G. Regensteiner, Mike Reidy, James Reimers, Renee Reinhart, John Reusing, Harriet Ricks, Valerie Ripley, Paris J. Roach, James Rochon, Bonny Rockette-Wagner, Ellen S. Rooney, Maria Rosario Araneta, Susan Roston, Jeanine Roumain, Patricia Rowe, Nancy D. Rowland, Debra Rowse, Robert J. Roy, Richard R. Rubin, Sofya Rubinchik, Debra Rubinstein, Stacy Rubtchinsky, Rosa Ruiz, Lily M.K. Rutledge, Donna H. Ryan, Lucy Ryder, Patrice Saab, Mohammed F. Saad, Monica Salazar, Alafia Samuels, Deborah A. Sanford, Sandra Sangster, Juliet Sanguily, Jessica Sansoucy, Julio V. Santiago, Ana Santiago, Alla Sapozhnikova, Andrew J. Sarkin, Christopher D. Saudek, David S. Schade, Jonathan Scheindlin, Pamela A. Schinleber, Emily B. Schroeder, Ann Schwartz, Dana Schweizer, Helen Seagle, Ellen W. Seely, Ann R. Semenske, Linda Semler, Willette Senter, Janet Sewenemewa, Harry Shamoon, Sue Shapiro, Ruth Shaw, Hanna Sherif, Amy R. Sherman, Thomas Shields, Alan R. Shuldiner, Angela Silverman, Marsha Simmons, Donald Simonson, Miranda Smart, Kenneth G. Smith, Lisa L. Smith, Kellie A. Smith, Carissa M. Smith, Fannie Smith, Clara M. Smith, Jean Smith, Marie Smith, Cheryl F. Smith, Judith E. Soberman, Elsayed Z. Soliman, Caren G. Solomon, Anthony Sosa, John Spandorfer, Jeanne Spellman, Chelsea Spencer, Preethi Srikanthan, Julia A. St Amant, Elizabeth Stamm, Sheila C. Steinke, Shawne Stephens, Christine Stevens, Kerry J. Stewart, Tamara Stich, Charlotte Stimpson, Greg Strylewicz, Emily Sullivan, Maria Swift, Kati Swift, Simona Szerdi Janesch, Sameh Tadros, Tonya Taylor, Lonnese Taylor, Laura Taylor, Karla A. Temple, Marinella Temprosa, Lisa Testaverde, Nopporn Thangthaeng, LeeLana Thomas, Celeste C. Thomas, April Thomas, Janet Tobian, Norica Tomuta, Darryl Tonemah, Jennifer Torio-Hurley, Gilda Trandafirescu, Dace Trence, Jennifer Truong, Elaine C. Tsai, Beverly Tseng, Richard T. Tulley, Heather Turgeon, Evonne Utsey, Gabriel Uwaifo, Gretchen E.H. Van, Brent VanDorsten, Pamela Vargo, Bertha Veciana, Karen Vejvoda, Elizabeth M. Venditti, Paula C. Vicknair, Veronica Villarreal, Elissa Violino, Kristine A. Viscovich, Elizabeth A. Walker, Tatiana Walker, Fredricka Walker-Murray, Amisha Wallia, James Warram, Debra Waters, Sheila Watson, Pamela G. Watson, Karol Watson, Valarie Weinzierl, Debra Wells-Thayer, Cormarie Wernimont, Madelyn L. Wheeler, Neil H. White, Tracy Whittington, Renee Wiggins, Wendi Wildman, Katherine V. Williams, Rachel Williams, Beverly Williams-Cleaves, Paula Williamson, Donald Williamson, Tara Wilson, Charlton Wilson, Rena R. Wing, Judith Wylie-Rosett, Kathy Xapthalamous, Robin E. Yamamoto, Michelle Yazzie, Gretchen Youssef, Jeffery J. Zachwieja, Ping Zhang, Zhuming Zhang, Elise Zimmerman, Joel Zonszein · 发表于：The Lancet Diabetes & Endocrinology · 年份：2025 · DOI：10.1016/s2213-8587(25)00022-1 · 被引用次数：31 · 研究领域：Diabetes Treatment and Management、Diabetes, Cardiovascular Risks, and Lipoproteins、Diabetes Management and Education