Receptor‐like kinase cleavage: molecular mechanism and regulatory functions in plants

作者：Meng Yu, Xiaotong Nie, Shaoying Ke, Li Li, Bin Li · 发表于：New Phytologist · 年份：2025 · DOI：10.1111/nph.70174 · 被引用次数：14 · 研究领域：Plant Reproductive Biology、Legume Nitrogen Fixing Symbiosis、Plant Parasitism and Resistance

Receptor-like kinases (RLKs) are essential in nearly all plant life activities. To date, most RLK research focuses on their plasma membrane functions as holoreceptors. This review introduces a distinct mechanism: RLK cleavage-regulated signal transduction in plants. We summarize cleavable RLKs and describe their cleavage forms, focusing on molecular mechanisms and functions for plant development and plant-microbe interactions. Notably, we emphasize that the released intracellular domain of RLKs translocates to the nucleus, mediating noncanonical signaling pathways. This review provides valuable insights into plant biology and underscores the significance of RLK cleavage in plant signaling.