The impact of financial toxicity on quality of life for survivors of primary brain tumour

作者：Jasmine Luttrell, Katarzyna Lion, Mark Blayne Pinkham, Louisa G. Collins, Tamara Ownsworth · 发表于：Journal of Cancer Survivorship · 年份：2025 · DOI：10.1007/s11764-025-01814-4 · 被引用次数：9 · 研究领域：Economic and Financial Impacts of Cancer、Childhood Cancer Survivors' Quality of Life、Cancer survivorship and care

PURPOSE: Despite the well-known impacts of financial hardship on cancer survivors, financial toxicity experienced in the context of brain tumour has received little attention. This study examined factors related to financial toxicity, and associations between financial toxicity, anxiety and quality of life (QoL) in this population. METHOD: Adults with primary brain tumour were recruited from hospital and community services as part of a telehealth psychological intervention study. They completed a telephone cognitive screener at pre-intervention, and the Comprehensive Score for Financial Toxicity-Functional Assessment of Chronic Illness Therapy (COST-FACIT), Generalised Anxiety Disorder-7 (GAD-7) and Functional Assessment of Cancer Therapy-Brain (FACT-Br) as part of a 6-week post-intervention assessment. RESULTS: Sixty brain tumour survivors (60% female; M age = 47.90, SD = 14.47) participated. Most of the sample (57%) experienced mild to moderate financial toxicity. Individuals with high-grade glioma reported significantly higher levels of financial toxicity compared to those with benign brain tumour. Greater perceived symptoms, lower global cognitive status and higher anxiety symptoms were significantly associated with higher financial toxicity. Financial toxicity contributed significant unique variance in QoL (4.2%), controlling for covariates. Anxiety symptoms partially mediated the relationship between financial toxicity and QoL (β = 0.24, CI 0.03, 0.55). CONCLUSIONS: Hig...