KMT2C deficiency drives transdifferentiation of double-negative prostate cancer and confer resistance to AR-targeted therapy

作者：Jiacheng Guo, Li Ni, Qiuli Liu, Zongyao Hao, Guanghui Zhu, Xuege Wang, Hanling Wang, Qiang Pan‐Hammarström, Bin Xu, Ying Han, Guoying Zhang, Yannan Lian, Wei Zhang, Yongqiang Gu, Naiheng Lin, Xin Zeng, Zige Jin, Weihua Lan, Jun Jiang, Dong Gao, Liang Dong, Huairui Yuan, Chaozhao Liang, Jun Qin · 发表于：Cancer Cell · 年份：2025 · DOI：10.1016/j.ccell.2025.04.002 · 被引用次数：24 · 研究领域：Prostate Cancer Treatment and Research、Cancer, Lipids, and Metabolism、Ubiquitin and proteasome pathways