New Evidence, Creative Insights, and Strategic Solutions: Advancing the Understanding and Practice of Diabetes Osteoporosis

作者：Bei Tao, Ximei Shen, Guangfei Li, Xi‐Yu Wu, Yuying Yang, Chunxiang Sheng, Yun Zhang, Ling Wang, Zhiyun Zhao, Qi Song, Dewen Yan, Sunjie Yan, Youjia Xu, Huijuan Yuan, Hou‐De Zhou, Jianmin Liu · 发表于：Journal of Diabetes · 年份：2025 · DOI：10.1111/1753-0407.70091 · 被引用次数：10 · 研究领域：Bone health and osteoporosis research、Bone Metabolism and Diseases、Parathyroid Disorders and Treatments

BACKGROUND: Diabetes osteoporosis is a debilitating condition that significantly impacts human health. However, it is often underdiagnosed and not addressed in a timely or appropriate manner. METHODS: Recent studies were reviewed to explore the roles of energy metabolism, sarcopeina, low-grade inflammation and gut microbiota in the development of diabetes osteoporosis. RESULTS: Osteoporosis in diabetic patients differs from primary osteoporosis. Novel biomarkers and risk factors that are biologically, physiologically, and pathologically linked to the development of diabetes osteoporosis are emerging, necessitating a shift in strategies for diagnosis, risk stratification, and prevention of diabetes osteoporosis. CONCLUSIONS: There is an urgent need to approach this disorder from a fresh perspective, initiating a range of basic research and clinical investigations.