Breaking the code: Using the Precision Health Model to guide research and clinical care

作者：Marilyn J. Hammer, Yvette P. Conley, Wendy A. Henderson, Nada Lukkahatai, Christine Miaskowski, Angela Starkweather, Susan W. Wesmiller · 发表于：Nursing Outlook · 年份：2025 · DOI：10.1016/j.outlook.2025.102396 · 被引用次数：3 · 研究领域：Health, Environment, Cognitive Aging、Nutrition, Genetics, and Disease、Cardiovascular Health and Risk Factors

BACKGROUND: Precision health is a person-centered approach to health and well-being that is operationalized through evaluating omics-level profiles and their associations with the exposome. A precision health approach addresses the challenge that "one size does not fit all" in the management of an individual's health. PURPOSE: The purpose of this white paper is to introduce a Precision Health Model and its application in research and clinical care. METHODS: An expert panel reviewed and synthesized the extant literature related to precision health, the current state of omics' science, and common exposome factors that influence the health/illness continuum. A case study provides the framework for the application of the Precision Health Model. DISCUSSION: Precision health and key domains are defined and serve as the platform for the development of the Precision Health Model. CONCLUSION: Application of the Precision Health Model will provide inclusive, equitable, person-centered research and clinical care.