The natural dihydrochalcone phloretin reduces lipid accumulation via downregulation of IIS and sbp-1 / SREBP pathways in HepG2 cells and Caenorhabditis elegans

作者：Qi Gu, Litao Wang, Mingyue Xu, Wanmei Zhou, Guosheng Liu, Haiting Tian, Thomas Efferth, Chenlu Wang, Yujie Fu · 发表于：Food & Function · 年份：2025 · DOI：10.1039/d5fo01105a · 被引用次数：7 · 研究领域：Birth, Development, and Health、Adipose Tissue and Metabolism、Circadian rhythm and melatonin

pathways. These findings suggest phloretin is a promising candidate for regulating lipid metabolism and preventing hyperlipidemia.