An International Delphi Consensus About Tumor Rupture During Robotic Partial Nephrectomy (Researching UnPredictable TUmor RupturE during Robotic Partial Nephrectomy—The RUPTURE Project)

作者：Riccardo Bertolo, Alessandro Antonelli, Axel Bex, Christopher B. Anderson, Riccardo Autorino, Neil Barber, Ketan K. Badani, Ravi Barod, Karim Bensalah, Jean‐Christophe Bernhard, Alberto Breda, Umberto Capitanio, Ben Challacombe, Simone Crivellaro, R. P. de Groote, Ithaar Derweesh, Antonio Galfano, Nina N. Harke, Jihad Kaouk, Alexander Kutikov, Kris Maes, Andrea Minervini, Maria Carmen Mir, Francesco Montorsi, Francesco Porpiglia, Jim Porter, Riccardo Schiavina, Stefan Siemer, Giuseppe Simone, Karim Touijer, Christophe Vaessen, Alessandro Volpe, Zhenjie Wu, Patricia Zondervan, Paul Russo, María J. Ribal, Alexandre Mottrie · 发表于：European Urology Open Science · 年份：2025 · DOI：10.1016/j.euros.2025.01.019 · 被引用次数：4 · 研究领域：Renal cell carcinoma treatment、Lung Cancer Diagnosis and Treatment、Cancer, Stress, Anesthesia, and Immune Response

While tumor rupture during robot-assisted partial nephrectomy (RAPN) is a rare occurrence, it poses significant oncological risks that can be mitigated through standardized definitions, identification of risk factors, and effective management strategies. Establishing clear guidelines for handling tumor rupture is essential for improving surgical outcomes and minimizing the risk of cancer spread. This Delphi consensus would serve as a foundation to encourage more structured research efforts that can produce higher levels of evidence. This panel’s recommendations offer a starting point by raising awareness of the risks associated with tumor rupture during RAPN and promoting the need for comprehensive studies. Tumor rupture during robot-assisted partial nephrectomy (RAPN) poses oncological risks, including potential malignant cell spread and recurrence. Despite these risks, standardized guidelines for defining, managing, and assessing risk factors of tumor rupture in RAPN are lacking. This Delphi consensus study aimed to frame the definition, risk factors, and oncological implications of tumor rupture in RAPN, as well as to propose management strategies. Using a modified Delphi method, a steering committee from multiple urological societies (the RUPTURE project) led a consensus-building study that followed the ACcurate COnsensus Reporting Document (ACCORD) checklist. A panel of international experts participated in a two-phase Delphi survey, rating their agreement with statement...