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DNMT1 is required for efficient DSB repair and maintenance of replication fork stability, and its loss reverses resistance to PARP inhibitors in cancer cells

作者:Wenjing Wu, Weijun Wu, Xiaojuan Xie, Jing Li, Yuan Gao, Li‐Min Xie, Caixia Zhong, Jianhong Xiao, Manbo Cai, Dong Yin, Kaishun Hu · 发表于:Oncogene · 年份:2025 · DOI:10.1038/s41388-025-03409-w · 被引用次数:7 · 研究领域:DNA Repair Mechanisms、PARP inhibition in cancer therapy、Cancer-related Molecular Pathways