Discovery of novel PI3KC2γ inhibitors with high potency, selectivity, and favorable pharmacokinetics for glycogen metabolism regulation

作者：Yi Zhong, Peili Jiao, Yuxi Wang, Beibei Mao, Han Huang, Shi Cheng, Xiaojiao Sun, Zhenming Liu, Liangren Zhang · 发表于：European Journal of Medicinal Chemistry · 年份：2025 · DOI：10.1016/j.ejmech.2025.117621 · 被引用次数：3 · 研究领域：Pancreatic function and diabetes、Metabolism, Diabetes, and Cancer、PI3K/AKT/mTOR signaling in cancer