Pseudoprogression on 68Ga-DOTATATE PET/CT in a Pediatric Patient With Neuroblastoma

作者：Xiaoya Wang, Siqi Li, Jun Liu, Jigang Yang · 发表于：Clinical Nuclear Medicine · 年份：2025 · DOI：10.1097/rlu.0000000000005818 · 被引用次数：9 · 研究领域：Neuroblastoma Research and Treatments、Neuroendocrine Tumor Research Advances、Lung Cancer Research Studies

A 6-year-old boy with neuroblastoma underwent a 68Ga-DOTATATE PET/CT scan to assess his therapeutic response. The results revealed significant DOTATATE uptake in the right mandible ramus compared with previous scans, indicating potential disease progression. In contrast, 123I-MIBG SPECT/CT imaging demonstrated the resolution of this lesion when compared with earlier MIBG images. This case highlights the possibility of pseudoprogression on 68Ga-DOTATATE PET/CT during the repair process of bone metastatic lesions in neuroblastoma.