Sentinel Lymph Node Biopsy in Early-Stage Breast Cancer: ASCO Guideline Update

作者：Ko Un Park, Mark R. Somerfield, Nirupama Anne, Muriel Brackstone, Alison Katherine Conlin, Henrique Lima Couto, Lynn Thacher Dengel, Andrea F. Eisen, Brittany E. Harvey, Jeffrey R. Hawley, Janice N. Kim, Nwamaka Ngozika Lasebikan, Elizabeth S. McDonald, Deepti Pradhan, Samantha Reiter Shams, Raymond B. Mailhot Vega, Alastair Mark Thompson, Mylin Ann Torres · 发表于：Journal of Clinical Oncology · 年份：2025 · DOI：10.1200/jco-25-00099 · 被引用次数：143 · 研究领域：Breast Cancer Treatment Studies、Breast Implant and Reconstruction、Breast Lesions and Carcinomas

ASCO Guidelines provide recommendations with comprehensive review and analyses of the relevant literature for each recommendation, following the guideline development process as outlined in the ASCO Guidelines Methodology Manual . ASCO Guidelines follow the ASCO Conflict of Interest Policy for Clinical Practice Guidelines . Clinical Practice Guidelines and other guidance (“Guidance”) provided by ASCO is not a comprehensive or definitive guide to treatment options. It is intended for voluntary use by clinicians and should be used in conjunction with independent professional judgment. Guidance may not be applicable to all patients, interventions, diseases or stages of diseases. Guidance is based on review and analysis of relevant literature, and is not intended as a statement of the standard of care. ASCO does not endorse third-party drugs, devices, services, or therapies and assumes no responsibility for any harm arising from or related to the use of this information. See complete disclaimer in Appendix 1 and 2 (online only) for more. PURPOSE To update the ASCO evidence-based recommendations on the use of sentinel lymph node biopsy (SLNB) in patients with early-stage breast cancer treated with initial surgery. METHODS ASCO convened an Expert Panel to develop updated recommendations based on a systematic literature review (January 2016-May 2024). RESULTS Eleven randomized clinical trials (14 publications), eight meta-analyses and/or systematic reviews, and one prospective cohor...