Aster tataricus L. f.: a review on the botany, phytochemistry, ethnopharmacology, pharmacology, toxicology and comprehensive utilization

作者：Xinyi Zhang, Meiqi Liu, Xiaozhuang Zhang, Lengleng Ma, Shiyi Song, Meitong Pan, Shumin Huang, Weichao Ren, Wei Ma · 发表于：Frontiers in Pharmacology · 年份：2025 · DOI：10.3389/fphar.2025.1581505 · 被引用次数：5 · 研究领域：Natural Antidiabetic Agents Studies、Phytochemistry and Biological Activities、Toxin Mechanisms and Immunotoxins

Aster tataricus L.f. ( A.tataricus ), a perennial herb of the genus Aster in the Asteraceae (Compositae) family. It is associated with a spicy, bitter, and warm nature and belongs to the Lung Meridian. The medicinal parts of A.tataricus are flowers, leaves, roots, and rhizomes. A.tataricus was first recorded in Shuo Wen under the alias “Zi Wan” (茈菀). Traditionally, it is utilised to clear lung qi, promote fluid flow, calm adverse-rising energy, relieve cough, resolve sputum, and regulate secretions. However, it is worth noting that A.tataricus has certain hepatotoxicity. Modern pharmacology indicates that A.tataricus can be used to treat various diseases, including those of the respiratory and urinary systems. In this review, all available information on A.tataricus was collected via academic databases such as PubMed, SciFinder Scholar, CNKI, iPlant, Google Scholar, Web of Science, GBIF, and Masterpieces of Traditional Chinese Medicine. To date, more than 200 metabolites have been isolated and characterized from A.tataricus , including terpenoids, flavonoids, polypeptides, and others. These compounds demonstrate a wide range of pharmacological activities, such as anti-inflammatory effects, antitussive and bronchodilatory properties, anticancer activity, antioxidant effects, treatment of osteolytic disorders, management of urinary system diseases, alleviation of acute lung injury, and enhancement of memory. Meanwhile, the different polarity extracts of A.tataricus also exhibit...