FOS-driven inflammatory CAFs promote colorectal cancer liver metastasis via the SFRP1-FGFR2-HIF1 axis

作者：Long Liu, Yuhao Ba, Shuaixi Yang, Aning Zuo, Shutong Liu, Yuyuan Zhang, Shuqin Xu, Siyuan Weng, Benyu Liu, Peng Luo, Quan Cheng, Jinhai Deng, Hui Xu, Yukang Chen, Chuhan Zhang, Xing Zhou, Yuqing Ren, Xinwei Han, Zhenyu Hou, Zaoqu Liu · 发表于：Theranostics · 年份：2025 · DOI：10.7150/thno.111625 · 被引用次数：21 · 研究领域：Fibroblast Growth Factor Research、Immune cells in cancer、Cancer, Hypoxia, and Metabolism

iCAFs as key regulators of tumor-stromal interactions and identifies SFRP1 as a potential therapeutic target in CRLM.