Immune checkpoint TIM-3 regulates microglia and Alzheimer’s disease

作者：Kimitoshi Kimura, Ayshwarya Subramanian, Zhuoran Yin, Ahad Khalilnezhad, Yufan Wu, Danyang He, Karen O. Dixon, Udbhav K. Chitta, Xiaokai Ding, Niraj Adhikari, Isabell Guzchenko, Xiaoming Zhang, Ruihan Tang, Thomas Pertel, Samuel A. Myers, Aastha Aastha, Masashi Nomura, Ghazaleh Eskandari‐Sedighi, Vasundhara Singh, Lei Liu, Conner Lambden, Kilian Kleemann, Neha Gupta, Jen‐Li Barry, Ana Durao, Yiran Cheng, Sebastian Silveira, Huiyuan Zhang, Aamir Suhail, Toni Delorey, Orit Rozenblatt–Rosen, Gordon J. Freeman, Dennis J. Selkoe, Howard L. Weiner, Mathew Blurton‐Jones, Carlos Cruchaga, Aviv Regev, Mario L. Suvà, Oleg Butovsky, Vijay K. Kuchroo · 发表于：Nature · 年份：2025 · DOI：10.1038/s41586-025-08852-z · 被引用次数：70 · 研究领域：Neuroinflammation and Neurodegeneration Mechanisms、Immune cells in cancer、Galectins and Cancer Biology