Advancements in the Application of the Intersection of Medicine and Engineering in Cancer Research

作者：Haitao Chen, Guan-Meng Zhang, Yuping Qian, Peng Yang, Xiaoli Li, Jiawen Wang, Jinlan Wang, Yu-xiang Hu, Xiao Han, Qinqiu Zhong, Xin Li, Yumeng Xie, Yukun Chen, Lijun Zhao, Qu Jing, Xiaofeng Shan, Yuguang Wang · 发表于：Cancer Nexus · 年份：2025 · DOI：10.1002/cnx2.70003 · 被引用次数：4 · 研究领域：Biomedical and Engineering Education、Biomedical Ethics and Regulation、Artificial Intelligence in Healthcare and Education

ABSTRACT Cancer research predominantly centers on diagnosis, treatment, and elucidation of underlying mechanisms. Nevertheless, the intricate nature of tumor genesis and development has rendered early diagnostic and therapeutic outcomes less than optimal, making tumor conquest a formidable challenge. The interdisciplinary fusion of medicine and engineering, termed the “intersection of medicine and engineering”, has emerged as a groundbreaking research paradigm, offering novel avenues for advancing cancer studies. As this interdisciplinary approach evolves, it has yielded numerous breakthroughs in cancer diagnosis, treatment, and mechanistic exploration. In this review, we summarize how the intersection of medicine and engineering propels the progress of cancer research by leveraging the combined strengths of medicine, bioinformatics, materials science, and artificial intelligence. This approach addresses the limitations of traditional cancer diagnostics and therapies, such as low sensitivity, poor efficacy, significant side effects, and the challenges associated with mechanistic exploration. Moreover, we highlight global cutting‐edge advancements and potential future directions in this field.