Thiourea Derivatives in Agrochemical Discovery and Development

作者：Qi Yi, Ping Sun, Xinyi Zhang, Hao Wang, Jian Wu · 发表于：Journal of Agricultural and Food Chemistry · 年份：2025 · DOI：10.1021/acs.jafc.5c00430 · 被引用次数：7 · 研究领域：Carbohydrate Chemistry and Synthesis、Polyamine Metabolism and Applications、Photosynthetic Processes and Mechanisms

N)C═S, is a significant organic sulfur compound characterized by the presence of a sulfur atom and two amino groups. Meanwhile, thiourea and isothiourea are reciprocal isomers. This structure facilitates the formation of a biologically active moiety, which is interconnected through double bonds between the sulfur atom and the nitrogen atoms. As a potent component in pesticide formulations, thiourea demonstrates efficacy in safeguarding crops against a variety of diseases by inhibiting the growth and reproduction of pathogens. This review aims to provide a comprehensive summary of thiourea derivatives exhibiting fungicidal, insecticidal, antiviral, herbicidal, and plant growth regulatory properties, with the objective of offering new perspectives for identifying innovative thiourea-based pesticides and elucidating their mechanisms of action.