Two telomere‐to‐telomere pig genome assemblies and pan‐genome analyses provide insights into genomic structural landscape and genetic adaptations

作者：Wencheng Zong, Li Chen, Dongjie Zhang, Yuebo Zhang, Jinbu Wang, Jinbu Wang, Xinhua Hou, Jie Chai, Yalong An, Ming Tian, Xinmiao He, Chengyi Song, Jun He, Xin Liu, L X Wang, L X Wang, Enrico D’Alessandro, Lixian Wang, Lixian Wang, Yulong Yin, Mingzhou Li, Di Liu, Jinyong Wang, Jinyong Wang, Longchao Zhang · 发表于：iMeta · 年份：2025 · DOI：10.1002/imt2.70013 · 被引用次数：13 · 研究领域：Animal Genetics and Reproduction、CRISPR and Genetic Engineering、Chromosomal and Genetic Variations

This study presented two high-precision telomere-to-telomere genome assemblies for Min and Rongchang pigs, including a detailed exploration of the telomeric and centromeric regions. By integrating pan-genome and multi-omics analyses, structural variations linked to genetic adaptation were identified, providing a valuable resource for advancing pig breeding and genetic improvement.