Discovery of 2,4-dianilinopyrimidine derivatives as novel p90 ribosomal S6 protein kinase (RSK) inhibitors

作者：Chun Han, Guo Chaohua, Xumei Zheng, Lin Zhao, Miao Sun, Jiandong Li, Shijun Wang, Zhang Zhang, Zhijun Wang, Lintao Wu · 发表于：European Journal of Medicinal Chemistry · 年份：2025 · DOI：10.1016/j.ejmech.2025.117590 · 研究领域：Melanoma and MAPK Pathways、Cancer Mechanisms and Therapy、Protein Kinase Regulation and GTPase Signaling