Efficacy of pulmonary rehabilitation on health-related quality of life in patients with interstitial lung disease as assessed by SF-36: a systematic review and meta-analysis

作者：Xing He, Jiaqi Ji, Zongmin Pei, Ting Zhou, Hong Fan, Lu Guo · 发表于：European Journal of Physical and Rehabilitation Medicine · 年份：2025 · DOI：10.23736/s1973-9087.25.08778-7 · 被引用次数：7 · 研究领域：Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis、Chronic Obstructive Pulmonary Disease (COPD) Research、Inflammatory Myopathies and Dermatomyositis

INTRODUCTION: The efficacy of pulmonary rehabilitation (PR) in improving health-related quality of life (HRQoL) in patients with interstitial lung disease (ILD) still have some unresolved issues. This study aimed to identify this gap by using the 36-Item Short Form Survey (SF-36) to assess the advantages and disadvantages of PR in improving the HRQoL of patients with ILD. EVIDENCE ACQUISITION: Self-controlled before-and-after interventional design research related to PR and ILD published in English were retrieved from PubMed, Embase, Web of Science, Scopus, Ovid, and Cochrane Library from inception to May 19, 2024. Data collected from the included studies were general clinical characteristics, study sample size, SF-36 physical component summary (PCS) score, SF-36 mental component summary (MCS) score, scores of the eight domains (physical function, role physical, bodily pain, general health, vitality, social function, role emotional, and mental health), PR time, and main elements of PR. Subgroup analysis was performed based on the PR time and ILD type. Sensitivity analysis was conducted by excluding one study at a time. Publication bias was assessed using Egger's Test, and the reliability of the studies was determined using the funnel plot and trim-and-fill method. Changes in SF-36 domain scores after PR were presented in a radar chart. EVIDENCE SYNTHESIS: Pooled analysis of 15 studies involving 1289 patients with ILD who underwent PR showed that the patients had significantly...