Distinct Functional MRI Connectivity Patterns and Cortical Volume Variations Associated with Repetitive Blast Exposure in Special Operations Forces Members

作者：Andrea Diociasi, Mary Alexis Iaccarino, Scott F. Sorg, Emily J. Lubin, Caroline Wisialowski, Amol Dua, Can Ozan Tan, Rajiv Gupta · 发表于：Radiology · 年份：2025 · DOI：10.1148/radiol.233264 · 被引用次数：10 · 研究领域：Traumatic Brain Injury Research、Radiation Dose and Imaging、Traumatic Brain Injury and Neurovascular Disturbances

value range, .01-.04). The predictive model helped accurately classify participants into high- and low-exposure groups based on fMRI data with 88.00 sensitivity (95% CI: 78.00, 98.00), 67% specificity (95% CI: 53.00, 81.00), and 73% accuracy (95% CI: 60.00, 86.00). Conclusion Repetitive blast exposure leads to distinct alterations in FC and cortical volume, which correlate with neurobehavioral symptoms. The predictive model suggests that even in the absence of observable anatomic changes, FC may indicate blast-related trauma. © RSNA, 2025