Therapeutic impact of dietary ginger supplementation in chickens experimentally infected with coccidia—anti-oxidant, biochemical, and pathological evaluations

作者：Alshimaa Saber, Amany Sayed Mawas, Atef M. Khalil, Ahmed Ibrahim Ahmed, Dina M. W. Shibat Elhamd, Esraa Ali, Ibrahim F. Rehan, Asmaa Elnagar, František Zigo, Mohammed Salah · 发表于：Frontiers in Veterinary Science · 年份：2025 · DOI：10.3389/fvets.2025.1511759 · 被引用次数：4 · 研究领域：Coccidia and coccidiosis research、Veterinary medicine and infectious diseases、Animal Nutrition and Physiology

Coccidiosis is a significant disease with economic implications. It causes high mortality and morbidity, often associated with weight loss. This study investigated the effects of ginger supplementation on antioxidant status, biochemical parameters, and intestinal tissue histopathology in experimentally induced coccidiosis. One hundred one-day-old broiler chicks (Ross) were purchased from a local hatchery. Birds were kept in a clean, well ventilated and disinfected shed. The birds were given non-pelleted diets and water ad libitum throughout the period of the study (25 days). The aqueous ginger was administered orally to the chicks of the four dietary groups via drinking water at concentrations of 6 gm/L of water. All biosecurity measures were adopted according to standard protocol. The chicks were allocated into five groups: control negative (CN), control positive (CP) was infected with 3 × 10 4 sporulated oocysts at day 14th of the experiment, the third group (GO) was given ginger only for 25 days, the fourth group (GB) was given ginger from day 4th to day 25th of the experiment, and the fifth group (GA) was given ginger from day 5th post infection to day 25th of the experiment. Ginger extract treatment reduced the fecal oocyst count in the infected group, particularly on day 10 post-infection. The alterations in differential leukocyte counts due to coccidial infection were ameliorated by ginger extract administration. Biochemically, compared to the infected group, ginger ( ...