Palladium-catalysed asymmetric regioselective hydroamination of dienoates

作者：Bao-Xin Liu, Xin-Ting Qin, Shi-Cun Li, Lei Zhu, Qin Ouyang, Wei Du, Ying‐Chun Chen · 发表于：Organic Chemistry Frontiers · 年份：2025 · DOI：10.1039/d5qo00402k · 被引用次数：5 · 研究领域：Oxidative Organic Chemistry Reactions、Asymmetric Hydrogenation and Catalysis、Catalytic C–H Functionalization Methods

An asymmetric formal 1,4-Michael addition-type reaction between δ-aryl-substituted dienoates and pyrazoles has been developed, through a Pd 0 π-Lewis base mediated protonation and allylic amination process.