A cross-sectional study comparing machine learning and logistic regression techniques for predicting osteoporosis in a group at high risk of cardiovascular disease among old adults

作者：Yuyi Peng, Chi Zhang, Bo Zhou · 发表于：BMC Geriatrics · 年份：2025 · DOI：10.1186/s12877-025-05840-w · 被引用次数：18 · 研究领域：Bone health and osteoporosis research、Bone Metabolism and Diseases、Biomarkers in Disease Mechanisms

BACKGROUND: Osteoporosis has become a significant public health concern that necessitates the application of appropriate techniques to calculate disease risk. Traditional methods, such as logistic regression,have been widely used to identify risk factors and predict disease probability. However,with the advent of advanced statistics techniques,machine learning models offer promising alternatives for improving prediction accuracy. What's more, studies that use risk factors and prediction models for osteoporosis in high-risk groups for cardiovascular diseases are scarce. We aimed to explore the risk factors and disease probability of osteoporosis by comparing logistic regression with four machine learning models. By doing so,we seek to provide insights into the most effective methods for osteoporosis risk assessment and contribute to the development of tailored prevention strategies at high risk of cardiovascular disease among old adults. METHODS: We carried out a cross-sectional investigation of a high-risk group in cardiovascular patients. A logistic regression model and four common machine learning methods,DT,RF,SVM,and XGBoost were implemented to create a prediction model using information from 211 participants who met the inclusion requirements. Metrics for calibration and discrimination were used to compare the models. RESULTS: In total,211 patients were enrolled. The AUCs were 0.751 for the logistic regression model,0.72 for the SVM model,0.70 for the random forest model...