Effective Components of Collaborative Care for Depression in Primary Care

作者：Hannah Schillok, Jochen Gensichen, Maria Panagioti, Jane Gunn, Lukas Junker, Karoline Lukaschek, Caroline Jung-Sievers, Philipp Sterner, Lukas Kaupe, Tobias Dreischulte, Mohammed K. Ali, Enric Aragonès, David B. Bekelman, Bea Herbeck Belnap, Robert M. Carney, Lydia Chwastiak, Peter Coventry, Karina W. Davidson, Maria L. Ekstrand, Alison Flehr, Susan Fletcher, Lars P. Hölzel, K.M.L. Huijbregts, Viswanathan Mohan, Vikram Patel, David Richards, Bruce L. Rollman, Chris Salisbury, Gregory E. Simon, Krishnamachari Srinivasan, Jürgen Unützer, Christina M. van der Feltz-Cornelis, Kenneth B. Wells, Thomas Zimmermann, Markus Bühner, POKAL Group, Markus Bühner, Tobias Dreischulte, Peter Falkai, Jochen Gensichen, Peter Henningsen, Caroline Jung-Sievers, Helmut Krcmar, Kirsten Lochbühler, Karoline Lukaschek, Gabriele Pitschel‐Walz, Barbara Prommegger, Antonius Schneider, Andrea Schmitt, Katharina Biersack, Vita Brišnik, Christopher Ebert, Julia Eder, Feyza Gökce, Carolin Haas, Lisa Pfeiffer, Lukas Kaupe, Jonas Raub, Philipp Reindl-Spanner, Petra Schönweger, Clara Teusen, Marie Vogel, Victoria von Schrottenberg, Jochen Vukas, Puya Younesi, Hannah Schillok · 发表于：JAMA Psychiatry · 年份：2025 · DOI：10.1001/jamapsychiatry.2025.0183 · 被引用次数：22 · 研究领域：Mental Health Treatment and Access、Digital Mental Health Interventions、Family Caregiving in Mental Illness

Importance: Collaborative care is a multicomponent intervention for patients with chronic disease in primary care. Previous meta-analyses have proven the effectiveness of collaborative care for depression; however, individual participant data (IPD) are needed to identify which components of the intervention are the principal drivers of this effect. Objective: To assess which components of collaborative care are the biggest drivers of its effectiveness in reducing symptoms of depression in primary care. Data Sources: Data were obtained from MEDLINE, Embase, Cochrane Library, PubMed, and PsycInfo as well as references of relevant systematic reviews. Searches were conducted in December 2023, and eligible data were collected until March 14, 2024. Study Selection: Two reviewers assessed for eligibility. Randomized clinical trials comparing the effect of collaborative care and usual care among adult patients with depression in primary care were included. Data Extraction and Synthesis: The study was conducted according to the IPD guidance of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses reporting guideline. IPD were collected for demographic characteristics and depression outcomes measured at baseline and follow-ups from the authors of all eligible trials. Using IPD, linear mixed models with random nested effects were calculated. Main Outcomes and Measures: Continuous measure of depression severity was assessed via validated self-report instruments at 4 to 6...