Pan‐cancer analysis shapes the understanding of cancer biology and medicine

作者：Xiaoping Cen, Yuanyuan Lan, Jiansheng Zou, Ruilin Chen, Can Hu, Yahan Tong, Chen Zhang, Jingyue Chen, Y Wang, Run Zhou, Weiwei He, Tianyu Lu, Fred Dubee, Dragomirka Jovic, Wei Dong, Qingqing Gao, Man Ma, Youyong Lu, Xue Fei Yu, Xiangdong Cheng, Yixue Li, Huanming Yang · 发表于：癌症：英文版 · 年份：2025 · DOI：10.1002/cac2.70008 · 被引用次数：23 · 研究领域：Cancer Genomics and Diagnostics、Bioinformatics and Genomic Networks、Ferroptosis and cancer prognosis

Advances in multi-omics datasets and analytical methods have revolutionized cancer research, offering a comprehensive, pan-cancer perspective. Pan-cancer studies identify shared mechanisms and unique traits across different cancer types, which are reshaping diagnostic and treatment strategies. However, continued innovation is required to refine these approaches and deepen our understanding of cancer biology and medicine. This review summarized key findings from pan-cancer research and explored their potential to drive future advancements in oncology.