Nano selenium and plant extracts supplementation enhanced reproductive performance of parity-2 sows

作者：Yuanfeng Li, Gu Yan, Xiang Ao · 发表于：Scientific Reports · 年份：2025 · DOI：10.1038/s41598-025-92981-y · 被引用次数：8 · 研究领域：Selenium in Biological Systems、Rabbits: Nutrition, Reproduction, Health、Moringa oleifera research and applications

To investigate the effects of nano selenium (nano-Se), curcumin (CUR), and glycyrrhiza extracts (GE) on reproductive performance, antioxidant and immune functions of primiparous sows and parity-2 sows, 54 primiparous sows (Landrace × Yorkshire) were randomly divided into three groups (18 sows per group): (1) CON group, basal diet (0.30 mg·kg −1 Se, sodium selenite); (2) CUR group, basal diet + 0.20 mg·kg −1 Se (nano-Se) + 300 mg·kg −1 CUR; (3) GE group, basal diet + 0.20 mg·kg −1 Se (nano-Se) + 500 mg·kg −1 GE. The trial lasted for approximately 180 days from day 90 of gestation of primiparous sows to parity-2 sows. There were no significant differences in reproductive performance among three groups ( p > 0.05), but the litter weight gain of piglets from primiparous sows in the GE group was 16.49% higher than that in the CON group ( p < 0.05). Compared with the CON group, the serum SOD and GSH-Px levels of primiparous sows in the GE group were significantly increased, and the MDA content was extremely decreased. The concentrations of serum IL-6 and IL-1β ( p < 0.05) of primiparous sows in the GE group were significantly lower than those in the CON group, and the serum IL-10 and TNF-α concentrations ( p < 0.05) was significantly higher. The combination of nano-Se and CUR decreased the serum IL-1β level and increased the TNF-α concentration ( p < 0.05). In conclusion, the addition of nano-Se along with CUR or GE in the diet of primiparous sows significantly increased the antiox...