Rapid Detection of Perfluorodecanoic Acid and Perfluorooctanesulfonic Acid in Foods Using a Molecularly Imprinted Poly( o -phenylenediamine)/Modified Glassy Carbon Electrode

作者：Ting Liu, Bolu Sun, Chun‐Yan Sang, Hua Cai, Hong Liu, Yuwei Liu, Gengsheng He · 发表于：Journal of Agricultural and Food Chemistry · 年份：2025 · DOI：10.1021/acs.jafc.5c00103 · 被引用次数：9 · 研究领域：Per- and polyfluoroalkyl substances research、Pharmacological Effects and Assays、Synthesis and Biological Evaluation

In the current work, a modified glassy carbon electrode (GCE) with excellent conductivity was prepared by drop-coating carboxymethyl cellulose (CMC) and multiwalled carbon nanotubes (MWCNTs) on the GCE surface. On this basis, two highly selective molecularly imprinted sensors (MIP@PFDA/modified GCE and MIP@PFOS/modified GCE) were separately obtained by in situ electropolymerization of o-phenylenediamine ( o -PD) with perfluorodecanoic acid (PFDA) and perfluorooctanesulfonic acid (PFOS) as templates. Under optimal conditions, sensitive quantification methods in the linearity ranges 0.1–1000 ng/mL (PFDA) and 0.05–900 ng/mL (PFOS) were developed via differential pulse voltammetry using [Fe(CN) 6 ] 3–/4– as a redox probe. The detection limit values of PFDA and PFOS were as low as 0.041 and 0.015 ng/mL, respectively. Both sensors also presented great stability and selectivity in coexistence with other interferences. Lastly, three food samples were utilized to verify the validity and applicability with recoveries of 89.97%–112.27%, confirming its potential for per- and polyfluoroalkyl substances (PFASs) monitoring in a complex matrix.