Synthesis and X-ray structure analysis of cytotoxic 2-picolylamino-type Hf IV -bis-chelated complexes

作者：Tiankun Zhao, Qi Zhang, Jinkui Zhao, Dikui Mei, Jing Ma, Isabel Correia, Zhongduo Yang, Sa‐Hyun Kim, Thomas Huhn · 发表于：Dalton Transactions · 年份：2025 · DOI：10.1039/d4dt02859g · 研究领域：Lanthanide and Transition Metal Complexes、Metal complexes synthesis and properties

complexes slowly hydrolyzed, releasing non-toxic phenolato ligands as the product of hydrolysis. Overall, these rare earth complexes, particularly [L1HfIVDipic4-Cl], show promising potential as novel anticancer agents with significant efficacy against human liver cancer cells and favorable selectivity profiles for further therapeutic development.