Cotton under heat stress: a comprehensive review of molecular breeding, genomics, and multi-omics strategies

作者：Tahira Luqman, Manzoor Hussain, Syed Riaz Ahmed, Iram Ijaz, Zahra Maryum, Sahar Nadeem, Zafran Khan, Sana Muhy Ud Din Khan, Mohammad Aslam, Yongming Liu, Muhammad Kashif Riaz Khan · 发表于：Frontiers in Genetics · 年份：2025 · DOI：10.3389/fgene.2025.1553406 · 被引用次数：17 · 研究领域：Research in Cotton Cultivation、Genetics and Plant Breeding、Insect Resistance and Genetics

Cotton is a vital fiber crop for the global textile industry, but rising temperatures due to climate change threaten its growth, fiber quality and yields. Heat stress disrupts key physiological and biochemical processes, affecting carbohydrate metabolism, hormone signaling, calcium and gene regulation and expression. This review article explores cotton's defense mechanism against heat stress, including epigenetic regulations and transgenic approaches, with a focus on genome editing tools. Given the limitations of traditional breeding, advanced omics technologies such as GWAS, transcriptomics, proteomics, ionomics, metabolomics, phenomics and CRISPR-Cas9 offer promising solutions for developing heat-resistant cotton varieties. This review highlights the need for innovative strategies to ensure sustainable cotton production under climate change.