Multicomponent Intervention for Distressed Informal Caregivers of People With Dementia

作者：Jojo Yan Yan Kwok, Daphne Sze Ki Cheung, Steven H. Zarit, Karen Siu-Lan Cheung, Bobo Hi Po Lau, VW Lou, Sheung‐Tak Cheng, Dolores Gallagher‐Thompson, Min Qian, Kee‐Lee Chou · 发表于：JAMA Network Open · 年份：2025 · DOI：10.1001/jamanetworkopen.2025.0069 · 被引用次数：11 · 研究领域：Dementia and Cognitive Impairment Research、Family Caregiving in Mental Illness、Intergenerational Family Dynamics and Caregiving

Importance: Multicomponent interventions for informal caregivers of people with dementia are urgently needed, but evidence regarding which components are most effective is lacking. Objective: To apply a multiphase optimization strategy to examine the effects of 5 psychosocial components of an intervention designed to support informal caregivers of people with dementia. Design, Setting, and Participants: In this assessor-blinded randomized clinical trial with a fractional factorial design, Chinese community-dwelling adults (aged ≥18 years) who were informal family caregivers of people with dementia were screened between July 2 and December 28, 2022, in Hong Kong. Eligible participants with elevated depression or caregiving burden were included and randomized to 1 of 16 experimental conditions. Assessments were conducted at baseline, 6 months, and 12 months. The last 12-month follow-up assessment was conducted on February 26, 2024. Interventions: The intervention involved a core component (dementia caregiving education) and 5 tested psychosocial components (self-care skills [SC], behavioral problem management [BPM], behavioral activation [BA], mindfulness-based intervention [MBI], and support group [SG]). Main Outcomes and Measures: Primary outcomes for each tested psychosocial component were physical health (12-item Short-Form Health Survey), caregiver burden (12-item Zarit Burden Interview) and stress (10-item Perceived Stress Scale), psychological well-being (Ryff Psychologi...