A versatile nanoplatform with excellent biofilm permeability and spatiotemporal ROS regulation for peri-implantitis treatment

作者：Zeyu Han, Ying Li, Xin Zhan, Ming Sun, Yan Liang, Mujie Yuan, Yong Sun, Jie Cao, Baodong Zhao, Li Fan · 发表于：Theranostics · 年份：2025 · DOI：10.7150/thno.108830 · 被引用次数：21 · 研究领域：Bone Tissue Engineering Materials、Dental Implant Techniques and Outcomes、Advanced biosensing and bioanalysis techniques

Given the pathogenesis of PI, this strategy rationally designed a multifunctional NP with antibacterial and anti-inflammatory functions via spatiotemporal ROS regulation. It provides a potentially novel approach for PI treatment, which may have a profound impact on improving the prognosis of patients with PI and advancing the field of implant dentistry.