Zwitterionic lipid nanoparticles for efficient siRNA delivery and hypercholesterolemia therapy with rational charge self-transformation

作者：Ruichen Zhao, Jing Guo, Ziqi Liu, Yusheng Zhang, Jiamin Zuo, Suxian Lv, Xianyu Li, Wenlong Yao, Xin Zhang · 发表于：Theranostics · 年份：2025 · DOI：10.7150/thno.111685 · 被引用次数：11 · 研究领域：RNA Interference and Gene Delivery、Advanced biosensing and bioanalysis techniques、Nanoparticle-Based Drug Delivery

These findings position ZwiLNPs as a promising platform for RNA interference therapies, particularly for hypercholesterolemia and other lipid-related disorders.