Atrial fibrillation burden in clinical practice, research, and technology development: a clinical consensus statement of the European Society of Cardiology Council on Stroke and the European Heart Rhythm Association

作者：Wolfram Doehner, Giuseppe Boriani, Tatjana Potpara, Carina Blomström‐Lundqvist, Rod Passman, Luciano A. Sposato, Dobromir Dobrev, Ben Freedman, Isabelle C. Van Gelder, Taya V. Glotzer, Jeff S. Healey, Theodoros Karapanayiotides, Gregory Y.H. Lip, José Luís Merino, George Ntaios, Renate B. Schnabel, Jesper Hastrup Svendsen, Emma Svennberg, Rolf Wachter, Karl Georg Hæusler, A. John Camm · 发表于：EP Europace · 年份：2025 · DOI：10.1093/europace/euaf019 · 被引用次数：98 · 研究领域：Atrial Fibrillation Management and Outcomes、Cardiac Arrhythmias and Treatments、Antiplatelet Therapy and Cardiovascular Diseases

Atrial fibrillation (AF) is one of the most common cardiac diseases and a complicating comorbidity for multiple associated diseases. Many clinical decisions regarding AF are currently based on the binary recognition of AF being present or absent with the categorical appraisal of AF as continued or intermittent. Assessment of AF in clinical trials is largely limited to the time to (first) detection of an AF episode. Substantial evidence shows, however, that the quantitative characteristic of intermittent AF has a relevant impact on symptoms, onset, and progression of AF and AF-related outcomes, including mortality. Atrial fibrillation burden is increasingly recognized as a suitable quantitative measure of intermittent AF that provides an estimate of risk attributable to AF, the efficacy of antiarrhythmic treatment, and the need for oral anticoagulation. However, the diversity of assessment methods and the lack of a consistent definition of AF burden prevent a wider clinical applicability and validation of actionable thresholds of AF burden. To facilitate progress in this field, the AF burden Consensus Group, an international and multidisciplinary collaboration, proposes a unified definition of AF burden. Based on current evidence and using a modified Delphi technique, consensus statements were attained on the four main areas describing AF burden: Defining the characteristics of AF burden, the recording principles, the clinical relevance in major clinical conditions, and implem...