Pharmacologically targeting fatty acid synthase-mediated de novo lipogenesis alleviates osteolytic bone loss by directly inhibiting osteoclastogenesis through suppression of STAT3 palmitoylation and ROS signaling

作者：Chunmei Xiu, Lei Zhang, Chenxi Zhang, Yanxia Zhang, Xi Luo, Ziyi Zhang, Hangkai Zhao, Kaizhong Ji, Zhiyuan Chen, Guangxu He, Jianquan Chen · 发表于：Metabolism · 年份：2025 · DOI：10.1016/j.metabol.2025.156186 · 被引用次数：15 · 研究领域：Bone health and treatments、Bone Metabolism and Diseases、Cancer, Lipids, and Metabolism