Dietary iron oxide (Fe2O3) nanoparticles modulate growth performance, body composition, mineral content and intestinal health of yellow catfish juveniles (Pelteobagrus fulvidraco)

作者：Xiaolei Wei, Zhi-Wei Hao, Yannis Kotzamanis, Tianhua Zhang, Zhibo Liu, Hong Yang, Zhi Luo · 发表于：Aquaculture Reports · 年份：2025 · DOI：10.1016/j.aqrep.2025.102739 · 被引用次数：4 · 研究领域：Aquaculture Nutrition and Growth、Fish Biology and Ecology Studies、Moringa oleifera research and applications

The present study investigated the growth performance, body composition, mineral content and intestinal health of yellow catfish juveniles fed different iron diets and explored the dietary Fe requirements for this fish species. Using iron oxide nanoparticles (Fe 2 O 3 NPs) as the Fe sources, we formulated six experimental diets with dietary Fe levels at 22.23, 28.28, 36.10, 44.53, 52.21, and 61.85 mg Fe/kg diet, respectively. Yellow catfish fed with 44.53 mg Fe/kg diet had the highest growth performance and feed utilization, while those fed 61.85 mg Fe/kg diet showed the lowest growth performance and feed utilization. Dietary Fe addition increased whole-body and intestinal Fe contents. Additionally, the addition of dietary Fe had an impact on whole-body crude protein, crude lipid, ash, calcium (Ca), magnesium (Mg), zinc (Zn), and manganese (Mn) contents, but did not whole-body moisture and copper (Cu) contents. Yellow catfish fed with 44.53 mg Fe/kg diet had an improvement in intestinal histology and an increase in expression of intestinal tight junction-related genes [ occludin and tight junction protein 1b ( zo-1b )] as well as antioxidant response genes [ superoxide dismutase 1 ( sod1 ), sod2 and catalase ( cat )], and had higher activities of antioxidant enzymes [CAT, total SOD (T-SOD) and total antioxidant capacity (T-AOC)]. However, malondialdehyde (MDA) content, and gene expression of glucose-regulated protein 78 ( grp78 ), eukaryotic translation initiation factor 2α (...