Effect of superficial cervical plexus nerve block with Ropivacaine or a combination of different adjuvants on perioperative analgesia and quality of postoperative recovery in patients undergoing radical thyroid cancer surgery under general anesthesia: a prospective randomized controlled trial

作者：Xiaoyu Kang, Li Caifen, Liuyu Lu, Xiaotong Qin, Yonghao Wang, Lu Yang, Li Ma, Shao‐Liang Zhu, Zheng Gong · 发表于：World Journal of Surgical Oncology · 年份：2025 · DOI：10.1186/s12957-025-03721-5 · 被引用次数：4 · 研究领域：Anesthesia and Pain Management、Cancer, Stress, Anesthesia, and Immune Response、Nausea and vomiting management

OBJECTIVE: To investigate the effect of ultrasound-guided bilateral superficial cervical plexus nerve blocks with Ropivacaine or a combination of different adjuvants on perioperative analgesia and quality of postoperative recovery in patients undergoing radical thyroid cancer surgery under general anesthesia with nerve monitoring without muscarinic maintenance. METHODS: A total of 140 patients undergoing elective radical thyroid cancer surgery were randomly divided into four groups, with 35 cases in each group: general anesthesia alone group (Group C), general anesthesia + Ropivacaine group (Group R), general anesthesia + Ropivacaine combined with dexmedetomidine group (Group R1), and general anesthesia + Ropivacaine combined with dexamethasone group (Group R2). The primary observation index were postoperative resting and active Visual Analogue Score. The secondary observation index were hemodynamics, intraoperative sedative and analgesic medication use, postoperative analgesic requirements, postoperative recovery indicators, Richards-Campbell Sleep Questionnaire scores, Quality of Postoperative Recovery-15 scores, and adverse reactions. RESULTS: Compared with group C, the resting and active VAS scores in group R were lower within 12 h after surgery (P < 0.05), the resting and active VAS scores in groups R1 and R2 were lower within 24 h after surgery (P < 0.05). Compared with group R, the VAS scores of patients in groups R1 and R2 were lower within 6 to 24 h after operation (...