From hard tissues to beyond: Progress and challenges of strontium-containing biomaterials in regenerative medicine applications

作者：Liyun Wang, Shengjie Jiang, Jialiang Zhou, Mazaher Gholipourmalekabadi, Yuan Cao, Kaili Lin, Yu Zhuang, Changyong Yuan · 发表于：Bioactive Materials · 年份：2025 · DOI：10.1016/j.bioactmat.2025.02.039 · 被引用次数：24 · 研究领域：Bone Tissue Engineering Materials、Orthopaedic implants and arthroplasty、Tissue Engineering and Regenerative Medicine

on critical biological processes such as osteogenesis, angiogenesis, immune modulation, matrix synthesis, mineralization, and antioxidative defence mechanisms. Then details the classification, properties, advantages, and limitations of Sr-containing biomaterials (SrBMs). Additionally, this review extends to the current applications of SrBMs in regenerative medicine for diverse tissues, including bone, cartilage, skeletal muscle, dental pulp, cardiac tissue, skin, hair follicles, etc. Moreover, the review addresses the challenges associated with current SrBMs and provides insights for their future designing and applications in regenerative medicine.