Integrative research on the mechanisms of acupuncture mechanics and interdisciplinary innovation

作者：Liang Yunshan, Chengli Xu, Zhang Peiming, Quan Haocheng, Liang Xudong, Liming Lu · 发表于：BioMedical Engineering OnLine · 年份：2025 · DOI：10.1186/s12938-025-01357-w · 被引用次数：28 · 研究领域：Acupuncture Treatment Research Studies、Myofascial pain diagnosis and treatment、Pain Management and Placebo Effect

As a traditional therapeutic approach, acupuncture benefits from modern biomechanics, which offers a unique perspective for understanding its mechanisms by investigating the mechanical properties of biological tissues and cells under force, deformation, and movement. This review summarizes recent advancements in the biomechanics of acupuncture, focusing on three main areas: the mechanical effects of acupuncture, the transmission mechanisms of mechanical signals, and the personalization and precision of acupuncture treatments. First, the review introduces the structural basis of the tissues involved in acupuncture; analyzes the mechanical responses of the skin, dermis, and subcutaneous tissues from needle insertion to point activation; and discusses how these responses impact acupuncture efficacy. Second, the phenomenon of mechanical coupling during acupuncture is discussed in detail, especially the role of connective tissues, including the wrapping and self-locking of collagen fibers, the remodeling of the cytoskeleton and the regulation of mitochondrial function triggered by acupuncture. Third, this article examines the mechanisms of mechanical signal transmission in acupuncture, explaining how mechanosensitive ion channels are activated during the procedure and subsequently initiate a cascade of biochemical responses. Finally, the review highlights the numerical simulation methods used in acupuncture, including the mechanical modeling of skin tissues, the exploration of the...