2025 European guideline on the management of Chlamydia trachomatis infections

作者：John Albert White, Nicole H. T. M. Dukers–Muijrers, Christian J. P. A. Hoebe, Chris Kenyon, Jonathan Ross, Magnus Unemo · 发表于：International Journal of STD & AIDS · 年份：2025 · DOI：10.1177/09564624251323678 · 被引用次数：46 · 研究领域：Reproductive tract infections research、Urinary Tract Infections Management、Cervical Cancer and HPV Research

Sexually transmitted Chlamydia trachomatis infections remain common globally and most frequently are asymptomatic. The 2025 European C. trachomatis guideline provides up-to-date guidance regarding indications for testing and treatment of C. trachomatis infections. It includes advice on urogenital and extragenital C. trachomatis testing including the use of self-collected specimens; recommendation to use only validated NAATs for diagnosis; and recommendation to treat all C. trachomatis infections with doxycycline as first line in preference to single-dose azithromycin regimens. The absence of evidence and limited value of broad screening in asymptomatic populations for C. trachomatis infections is also discussed.