Left atrioventricular coupling and left atrial abnormality in patients with acute myocardial infarction with and without hyperglycemia assessed with 3.0T cardiac magnetic resonance imaging feature tracking

作者：Pei‐Lun Han, Li Kang, Yu Jiang, Li Jiang, Xin Tang, Yingkun Guo, Yuan Li, Zhi-gang Yang · 发表于：Quantitative Imaging in Medicine and Surgery · 年份：2025 · DOI：10.21037/qims-24-1757 · 被引用次数：1 · 研究领域：Cardiovascular Function and Risk Factors、Cardiac Imaging and Diagnostics、Takotsubo Cardiomyopathy and Associated Phenomena

Background: The relationship between stress hyperglycemia and left atrial (LA) abnormality and left atrioventricular coupling in patients with acute myocardial infarction (AMI) has not been fully explored. This study aimed to assess the additive effect of hyperglycemia on LA phasic function and to investigate the atrioventricular interaction in patients with AMI via cardiac magnetic resonance imaging (MRI). Methods: ]. Univariate and multivariate linear regression analyses were employed to identify the independent factors related to LA phasic strains. Results: Compared with controls, patients with AMI had increased LAVI and decreased LAEF and LA strains (all P values <0.05), and the LA reservoir [LA total ejection fraction (LATEF) and εs] and conduit [LA passive ejection fraction (LAPEF) and εe] dysfunction was also present in those without LAE (all P values <0.05). Furthermore, εs and εe were significantly reduced in the aHGL group as compared with the aNGL group (both P values <0.001). After adjustments were made for confounding clinical factors, admission blood glucose level (aBGL) was independently and significantly associated with εs (β=-0.211; P=0.002) and εe (β=-0.215; P=0.001) in patients with AMI. After the introduction of left ventricular (LV) indicators into multivariable regression models, LV global longitudinal strain (GLS) was significantly associated with εs (β=-0.467; P<0.001) and εe (β=-0.455; P<0.001). Conclusions: Hyperglycemia was found to exacerbate LA re...