Dietary phytosterol supplementation mitigates renal fibrosis via activating mitophagy and modulating the gut microbiota

作者：Fan Yang, Yingjie Gao, Siyi Xie, Wenjing Yang, Qiyan Wang, Wenqian Ye, Lu Sun, Jiangtao Zhou, Xiue Feng · 发表于：Food & Function · 年份：2025 · DOI：10.1039/d4fo06043a · 被引用次数：11 · 研究领域：Liver Disease Diagnosis and Treatment、Chronic Kidney Disease and Diabetes、Autophagy in Disease and Therapy

the PINK1/Parkin pathway and modulate the gut microbiota, thereby alleviating renal fibrosis. The findings provide solid and significant implications for developing effective application of PS supplementation in the management of CKD, presenting novel concepts and approaches for research and clinical treatment.