Antiretroviral Therapy Adherence and Clinic Attendance Over Time Among People in Argentina Living with HIV and Lost to Care

作者：Omar Sued, Violeta J. Rodriguez, Stephen M. Weiss, María L. Alcaide, Diego Cecchini, Pedro Cahn, Isabel Cassetti, Chloe J. Kaminsky, Deborah L. Jones, The COPA Study Group · 发表于：International Journal of Behavioral Medicine · 年份：2025 · DOI：10.1007/s12529-025-10356-z · 被引用次数：3 · 研究领域：HIV/AIDS Research and Interventions、HIV/AIDS drug development and treatment、HIV, Drug Use, Sexual Risk

BACKGROUND: Although Argentina provides access to no cost HIV care, treatment adherence and retention in care remain suboptimal. This study aimed to explore factors associated with self-reported adherence and appointment attendance over time. METHOD: Participants (N = 360) were people living with HIV (PLWH) that were lost to care (i.e., three missed pharmacy pickups in the last 6 months, or had not attended a physician visit in the last 12 months). Participants were recruited from seven HIV clinics in four urban centers in Argentina and re-engaged in care. Demographic variables, predictors, i.e., alcohol use, self-efficacy, motivation, patient-provider communication, insurance type (private/public), and outcomes, i.e., missed infectious disease (ID) specialist appointments, other missed clinic and lab appointments, and self-reported adherence were assessed over 2 years. A logistic regression and Poisson regression model within a generalized linear mixed model framework was used to analyze the association between predictors, treatment adherence outcomes, and interactions with time. RESULTS: Following re-engagement in care, increased alcohol use was associated with lower odds of antiretroviral therapy adherence over time, increased odds of missing ID specialist appointments, and missed clinic/lab appointments. Self-efficacy was associated with better medication adherence and fewer missed ID specialist appointments over time. Similarly, both motivation and patient/provider commu...