Fabrication of tailored imprinted layer and cladded layer on magnetic nanomaterials with enhanced specificity for recognition of PFOS

作者：Yi Hao, Xiaoyi Chen, Kaili Wang, Xingyan Wang, Long Zhang, Haiyan Jing, Ruixia Gao, Sicen Wang · 发表于：Analytica Chimica Acta · 年份：2025 · DOI：10.1016/j.aca.2025.343799 · 被引用次数：8 · 研究领域：Per- and polyfluoroalkyl substances research、Analytical chemistry methods development、Fluoride Effects and Removal

Background Perfluorooctane sulfonate (PFOS) is a persistent organic pollutant with significant risks to ecosystems and human health. Magnetic molecularly imprinted polymers (MIPs) provide a promising solution for selectively extracting PFOS from contaminated water . However, while bifunctional monomer imprinting improves the imprinting effect by introducing diverse functional groups, it can also increase non-specific adsorption. To address this problem, a surface cladding strategy was applied after polymerization, forming an inert cladding layer to reduce non-specific binding and improve specificity. Results The magnetic MIPs with a cladding layer (Fe 3 O 4 @PFOS-cMIPs) exhibited enhanced adsorption performance, achieving a high adsorption capacity of 135.1 mg g −1 , an imprinting factor of 3.19, and a selectivity factor greater than 1.3, surpassing most reported PFOS-MIPs. The interactions between Fe 3 O 4 @PFOS-cMIPs and PFOS were confirmed to be a synergistic combination of electrostatic and hydrophobic interactions, as evidenced by FTIR analysis, zeta potential measurements, and pH studies. Additionally, Fe 3 O 4 @PFOS-cMIPs demonstrated excellent reusability, with stable performance across six adsorption-desorption cycles using a regeneration solution of acetone and NaCl. Furthermore, when coupled with LC-MS, Fe 3 O 4 @PFOS-cMIPs successfully detected trace levels of PFOS in complex environmental water samples. The method demonstrated high precision (RSD, 6.0 %), excelle...